pentobarbital will minimize the level or effect of midazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
The outcome of the resultant lessened blood levels of griseofulvin on therapeutic response hasn't been recognized. Even so, it would be preferable to avoid concomitant administration of such drugs.
pentobarbital will minimize the extent or result of prednisone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will minimize the level or effect of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
Barbiturates which includes pentobarbital are addictive and are actually historically misused and abused illegally as Road drugs. Pentobarbital abuse can lead to tolerance, dependence, and overdose, and lead to withdrawal symptoms for instance tremors, difficulty sleeping, and agitation upon discontinuation.
pentobarbital will lessen the level or outcome of ixabepilone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
Abrupt withdrawal of antiseizure drugs may well increase seizure frequency, withdraw pentobarbital little by little.
pentobarbital will lessen the level or effect of estrogens esterified by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
Barbiturates tend not to impair ordinary hepatic operate, but are revealed to induce liver microsomal enzymes, Therefore rising and/or altering check here the metabolism of barbiturates as well as other drugs. (See “DRUG INTERACTIONS” area).
Abuse of pentobarbital might cause dependence and habit and bring about overdose. In case of overdose instantly seek medical assistance or Call Poison Regulate.
pentobarbital will lessen the extent or effect of alfentanil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unknown.
pentobarbital will reduce the extent or result of nicardipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
pentobarbital will lower the extent or outcome of quetiapine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital will minimize the extent or impact of clozapine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.